betaxolol

Term ID

CHEBI:3082

Synonyms

1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol
1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol
1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol
betaxolol
betaxololum

Definition

A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydoxy is substituted by a 4-[2-(cyclopropylmethoxy)ethyl]phenyl group and one of the hydrogens attached to the amino group is substituted by isopropyl. It is a selective β₁-receptor blocker and is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease. It is also used to reduce non-fatal cardiac events in patients with heart failure.

References

cas:63659-18-7
drugbank:DB00195
drugcentral:356
hmdb:HMDB0014341
kegg.compound:C06849
kegg.drug:D07526
lincs.smallmolecule:LSM-1255
patent:DE2649605
patent:US4252984
pubmed:10891117
pubmed:1361581
pubmed:14971904
pubmed:15993593
pubmed:1865331
pubmed:2569884
reaxys:1991268
wikipedia.en:Betaxolol

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from betaxolol

Phenotype where environments contain betaxolol

Phenotype modified by environments containing betaxolol

Phenotype affecting betaxolol

Human Disease Model