21-deoxycortisol

Term ID

CHEBI:28697

Synonyms

• (1R,3aS,3bS,9aR,9bS,10S,11aS)-1-acetyl-1,10-dihydroxy-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
• 11-beta,17-alpha-dihydroxypregn-4-ene-3,20-dione
• 11beta,17-dihydroxypregn-4-ene-3,20-dione
• 11beta,17-dihydroxyprogesterone
• 11beta,17alpha-dihydroxypregn-4-ene-3,20-dione
• 11beta,17alpha-dihydroxyprogesterone
• 21-deoxycortisol
• 4-pregnene-11beta,17alpha-diol-3,20-dione
• pregn-4-ene-11beta,17alpha-diol-3,20-dione

Definition

A deoxycortisol that is 17ξ-pregn-4-ene-3,20-dione substituted by a β-hydroxy group at position 11 and an α-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency.

References

• cas:641-77-0
• foodb.food:FDB023283
• hmdb:HMDB0004030
• kegg.compound:C05497
• lipidmaps:LMST02030195
• pubmed:10731638
• pubmed:16551734
• pubmed:17456574
• pubmed:2531882
• pubmed:2555382
• pubmed:2614011
• pubmed:2827419
• pubmed:28499151
• pubmed:28610588
• pubmed:28774496
• pubmed:2986404
• pubmed:31450227
• pubmed:3258316
• pubmed:4372245
• pubmed:6310249
• pubmed:8055790
• pubmed:845476
• pubmed:8753277
• wikipedia.en:21-Deoxycortisol

Ontology

ChEBI  ( EBI )

Resources

CTD