cytarabine

Term ID

CHEBI:28680

Synonyms

• 1-beta-D-Arabinofuranosylcytosine
• 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
• 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
• ara-C
• arabinocytosine
• Arabinoside C
• citarabina
• cytarabine
• cytarabinum
• Cytosine arabinoside
• Cytosine-1-beta-D-arabinofuranoside
• cytosine-beta-D-arabinofuranoside

Definition

A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.

References

• Beilstein:89175
• CAS:147-94-4
• DrugBank:DB00987
• Drug_Central:770
• HMDB:HMDB0015122
• KEGG:C02961
• KEGG:D00168
• LINCS:LSM-5470
• PDBeChem:AR3
• PMID:15492802
• Reaxys:89175
• Wikipedia:Cytarabine

Ontology

ChEBI  ( EBI )

Resources

CTD