Search Ontology:
ChEBI

angiotensin I

Term ID
CHEBI:2718
Synonyms
  • angiotensin I
  • Angiotonin
  • Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
  • D-R-V-Y-I-H-P-F-H-L
  • DRVYIHPFHL
  • Hypertensin
  • L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidyl-L-leucine
  • L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe-L-His-L-Leu
  • pepsitensin
  • proangiotensin
Definition
A ten amino acid peptide formed by renin cleavage of angiotensinogen. Angiotensin I has no direct biological function except that high levels can stimulate catecholamine production. It is metabolized to its biologically active byproduct angiotensin II, a potent vasoconstrictor, by angiotensin converting enzyme (ACE) through cleavage of the two terminal amino acids.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
inverse is_tautomer_of
is_tautomer_of
Phenotype
Phenotype resulting from angiotensin I
Phenotype where environments contain angiotensin I
Phenotype modified by environments containing angiotensin I
Human Disease Model
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