Search Ontology:
ChEBI
adefovir
- Term ID
- CHEBI:2469
- Synonyms
-
- 9-(2-(Phosphonomethoxy)ethyl)adenine
- 9-(2-Phosphonylmethoxyethyl)adenine
- Adefovir
- DRG-0156
- GS 0393
- GS 393
- GS-0393
- HSDB 8079
- N-(2-Phosphonylmethoxyethyl)adenine
- PMEA
- {[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphonic acid
- Definition
- A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens has been replaced by a 2-(6-amino-9H-purin-9-yl)ethoxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(t-butoxycarbonyloxymethyl) ester (dipivoxil ester) prodrug is used to treat chronic hepatitis B viral infection.
- References
-
- cas:106941-25-7
- drugbank:DB00718
- kegg.compound:C11277
- kegg.drug:D02768
- pdb-ccd:5HG
- pubmed:10676990
- pubmed:11796353
- pubmed:14647052
- pubmed:14978283
- pubmed:15866657
- pubmed:22976988
- pubmed:24338503
- pubmed:27079793
- pubmed:27381944
- pubmed:27649318
- pubmed:27664568
- pubmed:27698751
- pubmed:27729626
- pubmed:27746441
- pubmed:27806120
- pubmed:27858892
- pubmed:27880997
- pubmed:27977591
- pubmed:28011962
- pubmed:28079295
- pubmed:28081595
- pubmed:28123560
- pubmed:28322924
- pubmed:28397817
- pubmed:28436380
- reaxys:3561094
- wikipedia.en:Adefovir
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from adefovir
Phenotype where environments contain adefovir
Phenotype modified by environments containing adefovir
Phenotype affecting adefovir
Human Disease Model