Search Ontology:
ChEBI
devimistat
- Term ID
- CHEBI:233197
- Synonyms
-
- 6,8-bis(benzylsulfanyl)octanoic acid
- CPI 613
- CPI-613
- CPI613
- devimistat
- devimistatum
- Definition
- A racemate comprising equimolar amounts of (6R)-6,8-bis(benzylsulfanyl)octanoic acid and its enantiomer, (6S)-6,8-bis(benzylsulfanyl)octanoic acid. It is an inhibitor of pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase enzymes, and currently in development for the treatment of pancreatic cancer and acute myeloid leukemia.
- References
-
- AGR:IND608318139
- CAS:95809-78-2
- DrugBank:DB12109
- PMID:27732654
- PMID:28495639
- PMID:29437791
- PMID:29879220
- PMID:31263141
- PMID:31512497
- PMID:31671803
- PMID:32345326
- PMID:34051378
- PMID:34750196
- PMID:34835640
- PMID:34906193
- PMID:35086846
- PMID:35172610
- PMID:35452495
- PMID:35675354
- PMID:36479231
- PMID:37115501
- PMID:37341164
- PMID:38151213
- PMID:38434963
- PMID:38483541
- PMID:38598967
- PMID:39088774
- PMID:39543742
- PMID:39675585
- PMID:39998953
- Wikipedia:Devimistat
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_part
-
- has_role
-
Phenotype
Phenotype resulting from devimistat
Phenotype where environments contain devimistat
Phenotype modified by environments containing devimistat
Phenotype affecting devimistat
Human Disease Model