enitociclib

Term ID

CHEBI:231682

Synonyms

• 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(methylsulfonimidoyl)methyl]pyridin-2-yl]pyridin-2-amine
• 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine
• BAY 1251152
• BAY-1251152
• BAY1251152
• enitociclib
• enitociclibum
• VIP 152
• VIP-152
• VIP152

Definition

A member of the class of aminopyridines that is pyridine substituted by {4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}amino, 4-fluoro-2-methoxyphenyl, and fluoro groups at positions 2, 4, and 5, respectively. It is an inhibitor of cyclin-dependent kinase 9 that exhibits antineoplastic activity.

References

• cas:1610408-97-3
• drugbank:DB17297
• kegg.drug:D12525
• pmc:PMC9430317
• pubmed:32866383
• pubmed:33227576
• pubmed:34062779
• pubmed:34264057
• pubmed:35046056
• pubmed:35485642
• pubmed:36376377
• pubmed:36399280
• pubmed:37272701
• pubmed:37552223
• pubmed:37719386
• pubmed:37882668
• pubmed:38886769
• pubmed:39222890
• wikipedia.en:Enitociclib

Ontology

ChEBI  ( EBI )