AZD5153

Term ID

CHEBI:231674

Synonyms

(3R)-4-(2-{4-[1-(3-methoxy[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy}ethyl)-1,3-dimethylpiperazin-2-one
(3R)-4-[2-[4-[1-(3-methoxy-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-4-piperidinyl]phenoxy]ethyl]-1,3-dimethyl-2-piperazinone
AZD 5153
AZD-5153

(all 4)

Definition

A member of the class of triazolopyridazines that is [1,2,4]triazolo[4,3-b]pyridazine substituted by methoxy and 4-(4-{2-[(2R)-2,4-dimethyl-3-oxopiperazin-1-yl]ethoxy}phenyl)piperidin-1-yl groups at positions 3 and 6, respectively. It is an orally bioavailable bivalent inhibitor of bromodomain-containing protein 4 with potential antineoplastic activity.

References

(all 20)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether N-methylpiperazine piperazinone piperidines triazolopyridazine

aromatic ether N-methylpiperazine piperazinone piperidines triazolopyridazine Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer bromodomain-containing protein 4 inhibitor

antineoplastic agent apoptosis inducer bromodomain-containing protein 4 inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from AZD5153

Phenotype where environments contain AZD5153

Phenotype modified by environments containing AZD5153

Phenotype affecting AZD5153

Human Disease Model