Search Ontology:
ChEBI
savolitinib
- Term ID
- CHEBI:231369
- Synonyms
-
- 1-[(1S)-1-(imidazo[1,2-a]pyridin-6-yl)ethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine
- 1-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine
- 3-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine
- AZD 6094
- AZD-6094
- AZD6094
- HM 5016504
- HM-5016504
- HMPL 504
- HMPL-504
- Orpathys
- savolitinib
- savolitinibum
- volitinib
- Definition
- A member of the class of triazolopyrazines that is 1H-[1,2,3]triazolo[4,5-b]pyrazine substituted by (1S)-1-(imidazo[1,2-a]pyridin-6-yl)ethyl and 1-methyl-1H-pyrazol-4-yl groups at positions 1 and 6, respectively. It is a highly selective MET tyrosine kinase inhibitor that is approved in China for advanced NSCLC with MET exon 14 skipping mutations.
- References
-
- CAS:1313725-88-0
- DrugBank:DB12048
- KEGG:D11139
- PDBeChem:V0L
- PMID:25148209
- PMID:25779944
- PMID:28644771
- PMID:29191878
- PMID:30952639
- PMID:31531204
- PMID:31564914
- PMID:32027846
- PMID:32469384
- PMID:33052556
- PMID:33125717
- PMID:33400845
- PMID:34455538
- PMID:34590028
- PMID:36333268
- PMID:36339926
- PMID:36551608
- PMID:36808891
- PMID:36809050
- PMID:36811415
- PMID:36846984
- PMID:36888921
- PMID:36944506
- PMID:37078211
- PMID:37293311
- PMID:37315260
- PMID:37564044
- PMID:37835402
- PMID:38023194
- PMID:38145112
- PMID:38181277
- PMID:38182507
- PMID:38276867
- PMID:38313385
- PMID:38380365
- PMID:38385995
- PMID:38525101
- PMID:38599970
- Wikipedia:Savolitinib
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from savolitinib
Phenotype where environments contain savolitinib
Phenotype modified by environments containing savolitinib
Human Disease Model