Search Ontology:
ChEBI
tert-butyloxycarbonyl-Leu-Arg-Arg-7-amino-4-methylcoumarin
- Term ID
- CHEBI:229561
- Synonyms
-
- 7-[(Boc-Leu-Arg-Arg)amino]-4-methylcoumarin
- Boc-L-Leu-L-Arg-L-Arg-7-amino-4-methylcoumarin
- Boc-L-Leu-L-Arg-L-Arg-AMC
- Boc-Leu-Arg-Arg-AMC
- Boc-LRR-AMC
- N-(tert-butoxycarbonyl)-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide
- Definition
- A tripeptide consisting of L-Leu-L-Arg-L-Arg carrying a Boc group at the N-terminal and a 7-amino-4-methylcoumarin group at the C-terminal. It is a fluorogenic substrate for detecting trypsin-like activity of the 26S proteasome or the 20S proteasome.
- References
-
- cas:109358-46-5
- pubmed:22615830
- pubmed:2276998
- pubmed:31473102
- pubmed:34943940
- pubmed:38397399
- pubmed:38974969
- pubmed:39210605
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from tert-butyloxycarbonyl-Leu-Arg-Arg-7-amino-4-methylcoumarin
Phenotype where environments contain tert-butyloxycarbonyl-Leu-Arg-Arg-7-amino-4-methylcoumarin
Phenotype modified by environments containing tert-butyloxycarbonyl-Leu-Arg-Arg-7-amino-4-methylcoumarin
Phenotype affecting tert-butyloxycarbonyl-Leu-Arg-Arg-7-amino-4-methylcoumarin
Human Disease Model