Search Ontology:
ChEBI
TA-1887
- Term ID
- CHEBI:229237
- Synonyms
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- (2R,3R,4S,5S,6R)-2-[3-(4-cyclopropylbenzyl)-4-fluoro-1H-indol-1-yl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
- (2R,3R,4S,5S,6R)-2-[3-[(4-cyclopropylphenyl)methyl]-4-fluoranyl-indol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triol
- 3-(4-cyclopropylbenzyl)-4-fluoro-1-beta-D-glucopyranosyl-1H-indole
- Definition
- A fluoroindole that is 1H-indole substituted by a beta-D-glucopyranosyl, 4-cyclopropylbenzyl, and fluoro groups at positions 1, 3 and 4, respectively. It is a highly potent and selective SGLT2 inhibitor, with antihyperglycemic effects in high-fat diet-fed KK mice.
- References
-
- CAS:1003005-29-5
- PDBeChem:KZ3
- PMID:21090651
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
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Phenotype
Phenotype resulting from TA-1887
Phenotype where environments contain TA-1887
Phenotype modified by environments containing TA-1887
Phenotype affecting TA-1887
Human Disease Model