Search Ontology:
ChEBI
fruquintinib
- Term ID
- CHEBI:229221
- Synonyms
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- 6-[(6,7-dimethoxyquinazolin-4-yl)oxy]-N,2-dimethyl-1-benzofuran-3-carboxamide
- fruquintinib
- fruquintinibum
- Definition
- A member of the class of quinazolines that is quinazoline substituted by [2-methyl-3-(methylcarbamoyl)-1-benzofuran-6-yl]oxy, methoxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a highly potent and selective inhibitor of VEGFR 1, 2 and 3 (IC50 = 33, 0.35, and 35 nM) used for the treatment of metastatic colorectal cancer.
- References
-
- CAS:1194506-26-7
- DrugBank:DB11679
- KEGG:D11977
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from fruquintinib
Phenotype where environments contain fruquintinib
Phenotype modified by environments containing fruquintinib
Phenotype affecting fruquintinib
Human Disease Model