repotrectinib

Term ID

CHEBI:229220

Synonyms

(7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one
Augtyro
repotrectinib
repotrectinibum
TPX 0005
TPX-0005
TPX0005

(all 7)

Definition

An azamacrocycle with formula C18H18FN5O2. It is a tyrosine kinase inhibitor (highly potent against ROS1, TRKA-C, and ALK) used for the treatment of locally advanced or metastatic ROS1-positive non-small cell lung cancer.

References

(all 30)

Ontology

ChEBI ( EBI )

Relationships

is a type of: azamacrocycle cyclic ether monofluorobenzenes pyrazolopyrimidine secondary carboxamide

azamacrocycle cyclic ether monofluorobenzenes pyrazolopyrimidine secondary carboxamide Show first 5 Terms
has_role: antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor

antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from repotrectinib

Phenotype where environments contain repotrectinib

Phenotype modified by environments containing repotrectinib

Phenotype affecting repotrectinib

Human Disease Model