bafilomycin A1

Term ID

CHEBI:22689

Synonyms

(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-{(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl]-3-hydroxypentan-2-yl}-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one

Definition

The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: cyclic hemiketal macrolide antibiotic oxanes

cyclic hemiketal macrolide antibiotic oxanes Show first 5 Terms
has_role: apoptosis inducer autophagy inhibitor bacterial metabolite EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor ... Show All 9 Terms

apoptosis inducer autophagy inhibitor bacterial metabolite EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor ferroptosis inhibitor fungicide potassium ionophore toxin Show first 5 Terms

Phenotype

Phenotype resulting from bafilomycin A1

Phenotype where environments contain bafilomycin A1

Phenotype modified by environments containing bafilomycin A1

Human Disease Model