Search Ontology:
ChEBI

6-O-methylguanine

Term ID
CHEBI:20689
Synonyms
  • 2-Amino-6-methoxypurine
  • 6-Methoxy-1H-purine-2-amine
  • 6-methoxy-7H-purin-2-amine
  • 6-Methoxyguanine
  • O(6)-methylguanine
  • O-(6)-Methylguanine
Definition
A methylguanine in which the methyl group is positioned on the oxygen at position 6. Formed in DNA by alkylation of the oxygen atom of guanine, most often by N-nitroso compounds and sometimes due to methylation by other compounds such as endogenous S-adenosylmethionine, it base-pairs to thymine rather than cytidine, causing a G:C to A:T transition in DNA.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from 6-O-methylguanine
Phenotype where environments contain 6-O-methylguanine
Phenotype modified by environments containing 6-O-methylguanine
Human Disease Model
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