carbovir

Term ID

CHEBI:202940

Synonyms

(+-)-carbovir
2-amino-9-[rel-(1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl]-1,9-dihydro-6H-purin-6-one
2-amino-9-[rel-(1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl]-9H-purin-6-ol
carbovir
cis-(+-)-2-amino-1,9-dihydro-9-(4-(hydroxymethyl)-2-cyclopenten-1-yl)-6H-purin-6-one
cis-2-amino-1,9-dihydro-9-(4-(hydroxymethyl)-2-cyclopenten-1-yl)-6H-purin-6-one
cis-2-amino-9-(4-hydroxymethylcyclopent-2-enyl)-9H-purin-6-ol

Definition

Cyclopent-2-en-1-ylmethanol in which the 4-position is substituted by a 2-amino-6-hydroxy-9H-purin-9-yl group such that the two substitutents on the cyclopentene ring are in a cis relationship. The (-)-enantiomer, also known as carbovir, is a potent inhibitor of HIV replication replication in cell cultures.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 2-aminopurines

2-aminopurines Show first 5 Terms
has subtype: (-)-carbovir

(-)-carbovir Show first 5 Terms
has_role: HIV-1 reverse transcriptase inhibitor

HIV-1 reverse transcriptase inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from carbovir

Phenotype where environments contain carbovir

Phenotype modified by environments containing carbovir

Phenotype affecting carbovir

Human Disease Model