CH-223191

Term ID

CHEBI:195599

Synonyms

1-methyl-N-{2-methyl-4-[(2-methylphenyl)diazenyl]phenyl}-1H-pyrazole-5-carboxamide
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide
2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide
CH 223191
CH223191

Definition

A secondary carboxamide resulting from the formal condensation of the carboxy group of 1-methyl-1H-pyrazole-5-carboxylic acid with the amino group of 2-methyl-4-[(2-methylphenyl)diazenyl]aniline. It is a potent aryl hydrocarbon receptor (AhR) antagonist (IC₅₀ = 30 nM).

References

cas:301326-22-7
lincs.smallmolecule:LSM-37014
pubmed:16540597
pubmed:20634293
pubmed:21967751
pubmed:30793600
pubmed:30987575
pubmed:31358358
pubmed:32416216
pubmed:35371054
pubmed:35687264
pubmed:35721314
pubmed:35788946
pubmed:37322333
pubmed:37352327
pubmed:37373144
pubmed:37539825

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from CH-223191

Phenotype where environments contain CH-223191

Phenotype modified by environments containing CH-223191

Phenotype affecting CH-223191

Human Disease Model