Search Ontology:
ChEBI
poziotinib
- Term ID
- CHEBI:195559
- Synonyms
-
- 1-(4-{[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxy}piperidin-1-yl)prop-2-en-1-one
- 1-[4-[[4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one
- HM 781-36B
- Definition
- A member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, [1-(prop-2-enoyl)piperidin-4-yl]oxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a potent and irreversible tyrosine kinase inhibitor targeting EGFR and HER2 with exon 20 insertion mutations.
- References
-
- CAS:1092364-38-9
- Chemspider:30687714
- DrugBank:DB12114
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 9 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from poziotinib
No data available
Phenotype where environments contain poziotinib
No data available
Phenotype modified by environments containing poziotinib
No data available
Phenotype affecting poziotinib
No data available
Human Disease Model
No data available