3-BrB-PP1

Term ID

CHEBI:194136

Synonyms

1-tert-butyl-3-(3-bromobenzyl)-1H-pyrazolo[3,4-d]pyrimidine-4-amine
3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
3-[(3-bromophenyl)methyl]-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
3-[(3-bromophenyl)methyl]-1-tert-butyl-pyrazolo[3,4-d]pyrimidin-4-amine
3-[(3-bromophenyl)methyl]-1-tert-butylpyrazolo[3,4-d]pyrimidin-4-amine
3BrB-PP1
4-amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine

Definition

A member of the class of pyrazolopyrimidines that is pyrazolo[3,4-d]pyrimidin-4-amine bearing additional tert-butyl and 3-bromobenzyl substituents at positions 1 and 3 respectively. It is an ATP-competitive inhibitor of CDPK1 and AKT kinase.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amine bromobenzenes pyrazolopyrimidine

aromatic amine bromobenzenes pyrazolopyrimidine Show first 5 Terms
has_role: antiparasitic agent EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor

antiparasitic agent EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from 3-BrB-PP1

Phenotype where environments contain 3-BrB-PP1

Phenotype modified by environments containing 3-BrB-PP1

Human Disease Model