Search Ontology:
ChEBI
XL413
- Term ID
- CHEBI:189662
- Synonyms
-
- 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one
- BMS 863233
- BMS-863233
- BMS863233
- XL 413
- XL-413
- Definition
- A benzofuropyrimidine that is 3,4-dihydro[1]benzofuro[3,2-d]pyrimidine substituted by (2S)-pyrrolidin-2-yl, oxo and chloro groups at positions 2, 4, and 8, respectively. It is a potent ATP competitive inhibitor of Cdc7 kinase (IC50 = 3.4 nM) and exhibits anticancer properties.
- References
-
- CAS:1169558-38-6
- Chemspider:28508270
- DrugBank:DB12357
- PDBeChem:0SX
- PMID:22560567
- PMID:23064647
- PMID:25412417
- PMID:26589264
- PMID:28560864
- PMID:29713760
- PMID:30802412
- PMID:32355159
- PMID:32521228
- PMID:34307771
- Wikipedia:XL-413
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from XL413
Phenotype where environments contain XL413
Phenotype modified by environments containing XL413
Human Disease Model