Search Ontology:
ChEBI
molnupiravir
- Term ID
- CHEBI:180653
- Synonyms
-
- beta-D-N(4)-hydroxycytidine-5'-isopropyl ester
- EIDD 1931 5'-isopropylester
- EIDD 2801
- EIDD-2801
- MK-4482
- molnupiravir
- molnupiravirum
- N(4)-hydroxycytidine 5'-isopropylester
- N-hydroxy-5'-O-(2-methylpropanoyl)-3,4-dihydrocytidine
- {(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]tetrahydrofuran-2-yl}methyl 2-methylpropanoate
- Definition
- A nucleoside analogue that is N(4)-hydroxycytidine in which the 5'-hydroxy group is replaced by a (2-methylpropanoyl)oxy group. It is the prodrug of the active antiviral ribonucleoside analog N(4)-hydroxycytidine (EIDD-1931), has activity against a number of RNA viruses including SARS-CoV-2, MERS-CoV, and seasonal and pandemic influenza viruses. It is currently in phase III trials for the treatment of patients with COVID-19.
- References
-
- CAS:2349386-89-4
- CAS:2492423-29-5
- Chemspider:84400552
- KEGG:D11943
- PMCID:PMC8461366
- PMID:31645453
- PMID:31910262
- PMID:31945316
- PMID:32253226
- PMID:32503814
- PMID:32714193
- PMID:33030468
- PMID:33273742
- PMID:33290476
- PMID:33561864
- PMID:33588727
- PMID:33649113
- PMID:33664631
- PMID:33863887
- PMID:33902254
- PMID:33961695
- PMID:33989635
- PMID:34056192
- PMID:34118236
- PMID:34244768
- PMID:34271264
- PMID:34337170
- PMID:34381216
- PMID:34425873
- PMID:34509661
- PMID:34518697
- PMID:34571361
- Wikipedia:Molnupiravir
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_functional_parent
-
- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from molnupiravir
Phenotype where environments contain molnupiravir
Phenotype modified by environments containing molnupiravir
Phenotype affecting molnupiravir
Human Disease Model