Search Ontology:
ChEBI

amperozide

Term ID
CHEBI:180480
Synonyms
  • 4-(4,4-bis(p-fluorophenyl)butyl)-N-ethyl-1-piperazinecarboxamide
  • 4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide
  • amperozida
  • amperozide
  • amperozidum
Definition
A member of the class of ureas that is urea in which three of the four hydrogens are replaced by ethyl and 4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl groups. An atypical antipsychotic which was in clinical development for the treatment of schizophrenia and substance-related disorders. It is a potent 5-HT2A antagonist and used in veterinary medicine because of its sedative effect on pigs.
References
  • cas:75558-90-6
  • chemspider:66062
  • drugbank:DB08927
  • drugcentral:193
  • hmdb:HMDB0248358
  • lincs.smallmolecule:LSM-3159
  • patent:EP0517787
  • patent:WO9112805
  • pubmed:10068147
  • pubmed:10512574
  • pubmed:10627067
  • pubmed:10975635
  • pubmed:12127016
  • pubmed:12213521
  • pubmed:18666714
  • pubmed:19850474
  • pubmed:2106131
  • pubmed:2111999
  • pubmed:2154737
  • pubmed:2224491
  • pubmed:2304894
  • pubmed:2304896
  • pubmed:2406715
  • pubmed:24134630
  • pubmed:2746728
  • pubmed:3751811
  • pubmed:7879876
  • pubmed:8050470
  • pubmed:8060520
  • pubmed:8255902
  • pubmed:8405119
  • pubmed:9443541
  • pubmed:9597673
  • pubmed:9631953
  • pubmed:9686999
  • wikipedia.en:Amperozide
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from amperozide
Phenotype where environments contain amperozide
Phenotype modified by environments containing amperozide
Phenotype affecting amperozide
Human Disease Model