RSL5

Term ID

CHEBI:176418

Synonyms

2-methoxyethyl (4S,7S)-7-(4-chlorophenyl)-4-(2-fluorophenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate

Definition

A quinolone that is 4,6,7,8-tetrahydroquinolin-5(1H)-one substituted by methyl, (2-methoxyethoxy)carbonyl, 2-fluorophenyl and 4-chlorophenyl groups at positions 2, 3, 4 and 7, respectively (the 4S,7S-stereoisomer). It is an inhibitor of voltage-dependent anion channel 3 (VDAC3) and a ferroptosis inducer.

References

PMID:18355723

Ontology

ChEBI ( EBI )

Relationships

is a type of: 2-methoxyethyl ester monochlorobenzenes monofluorobenzenes quinolone

2-methoxyethyl ester monochlorobenzenes monofluorobenzenes quinolone Show first 5 Terms
has_role: antineoplastic agent ferroptosis inducer voltage-dependent anion channel inhibitor

antineoplastic agent ferroptosis inducer voltage-dependent anion channel inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from RSL5

Phenotype where environments contain RSL5

Phenotype modified by environments containing RSL5

Human Disease Model