dutomycin

Term ID

CHEBI:171673

Synonyms

(2R,3S,6S)-6-{[(1R,4aS,12aR)-3-acetyl-2,4a,6,12a-tetrahydroxy-9-methoxy-11-methyl-4,5,7,10-tetraoxo-1,4,4a,5,7,10,12,12a-octahydrotetracen-1-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 2,6-dideoxy-4-O-[(2Z,4R)-2,4-dimethylhept-2-enoyl]-3-C-methyl-alpha-L-xyl

Definition

An anthracycline antibiotic of formula C44H54O17 isolated from Streptomyces species. It directly binds to the human serine protease inhibitor B6 (SERPINB6), inducing autophagy and apoptosis.

References

(all 5)

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 1,4-benzoquinones anthracycline antibiotic carbohydrate-containing antibiotic carbopolycyclic compound disaccharide derivative ... Show All 10 Terms

1,4-benzoquinones anthracycline antibiotic carbohydrate-containing antibiotic carbopolycyclic compound disaccharide derivative enoate ester enol ether phenols tertiary alpha-hydroxy ketone Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer autophagy inducer bacterial metabolite

antineoplastic agent apoptosis inducer autophagy inducer bacterial metabolite Show first 5 Terms

Phenotype

Phenotype resulting from dutomycin

Phenotype where environments contain dutomycin

Phenotype modified by environments containing dutomycin

Phenotype affecting dutomycin

Human Disease Model