Search Ontology:
ChEBI

tesevatinib

Term ID
CHEBI:167674
Synonyms
  • 7-{[(3aR,5R,6aS)-2-methyl-octahydrocyclopenta[c]pyrrol-5-yl]methoxy}-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine
  • EXEL 7647
  • EXEL-7647
  • EXEL7647
  • KD 019
  • KD-019
  • KD019
  • N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-{[(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy}quinazolin-4-amine
  • tesevatinib
  • tesevatinibum
  • XL 647
  • XL-647
  • XL647
(all 13)
Definition
A member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, methoxy, and [(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy groups at positions 4, 6 and 7, respectively. It is a multi-target tyrosine kinase inhibitor of EGFR, ErbB2, KDR, Flt4 and EphB4 and exhibits anti-cancer properties.
References
(all 16)
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from tesevatinib
Phenotype where environments contain tesevatinib
Phenotype modified by environments containing tesevatinib
Phenotype affecting tesevatinib
Human Disease Model
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