Search Ontology:
ChEBI
Glu-Gly-Arg-chloromethylketone
- Term ID
- CHEBI:157651
- Synonyms
-
- chloromethylketone-EGR
- EGR-chloromethylketone
- EGR-CMK
- EGRCK
- Glu-Gly-Arg-chloromethylketone
- glutamyl-glycyl-arginine chloromethyl ketone
- H-Glu-Gly-Arg-CH2Cl
- H-Glu-Gly-Arg-chloromethylketone
- L-alpha-glutamyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]glycinamide
- L-Glu-Gly-L-Arg-chloromethylketone
- Definition
- A tripeptide composed of L-glutamic acid, glycine and L-arginine joined in sequence by peptide linkages and in which the carboxy terminus is substituted by a chloroacetyl group. It is a potent and irreversible inhibitor of urokinase-type plasminogen activator (uPA) and factor Xa.
- References
-
- cas:65113-67-9
- pubmed:10805774
- pubmed:1310986
- pubmed:17563121
- pubmed:1828371
- pubmed:18803401
- pubmed:19243318
- pubmed:21454081
- pubmed:24900505
- pubmed:29164060
- pubmed:36780344
- pubmed:7918392
- pubmed:8900128
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from Glu-Gly-Arg-chloromethylketone
Phenotype where environments contain Glu-Gly-Arg-chloromethylketone
Phenotype modified by environments containing Glu-Gly-Arg-chloromethylketone
Phenotype affecting Glu-Gly-Arg-chloromethylketone
Human Disease Model