Search Ontology:
ChEBI
G-15
- Term ID
- CHEBI:156295
- Synonyms
-
- (3aS,4R,9bR)-4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
- G 15
- G15
- Definition
- An organic heterotricyclic compound that is 3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline substituted by a 6-bromo-1,3-benzodioxol-5-yl group at position 4 (the 3aS,4R,9bR-stereoisomer). It is a high affinity and selective GPER1 receptor antagonist (Ki = 20 nM) which inhibits the anti-depressive effects of estrogen in vivo.
- References
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from G-15
Phenotype where environments contain G-15
Phenotype modified by environments containing G-15
Phenotype affecting G-15
Human Disease Model