Search Ontology:
ChEBI
zolasartan
- Term ID
- CHEBI:149761
- Synonyms
-
- 1-((3-bromo-2-(o-1H-tetrazol-5-ylphenyl)-5-benzofuranyl)methyl)-2-butyl-4-chloroimidazole-5-carboxylic acid
- 1-({3-bromo-2-[2-(1H-tetrazol-5-yl)phenyl]-1-benzofuran-5-yl}methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid
- GR 117289
- GR 117289C
- GR-117289
- GR-117289C
- GR117289
- GR117289C
- zolasartan
- zolasartanum
- Definition
- A member of the class of 1-benzofurans that is 3-bromo-1-benzofuran which is substituted by a 2-(1H-tetrazol-5-yl)phenyl group at position 2 and by a (2-butyl-5-carboxy-4-chloro-1H-imidazol-1-yl)methyl group at position 5. It is an angiotensin II receptor type 1 (AT1) antagonist and was in clinical trials for the treatment of hypertension (now discontinued).
- References
-
- cas:145781-32-4
- pubmed:10473295
- pubmed:10579749
- pubmed:11156121
- pubmed:11690530
- pubmed:1467838
- pubmed:7587961
- pubmed:7786519
- pubmed:8012689
- pubmed:8155901
- pubmed:8358571
- pubmed:8469769
- pubmed:8495237
- pubmed:8836613
- pubmed:9088589
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from zolasartan
Phenotype where environments contain zolasartan
Phenotype modified by environments containing zolasartan
Phenotype affecting zolasartan
Human Disease Model