Search Ontology:
ChEBI

bempedoic acid

Term ID
CHEBI:149601
Synonyms
  • 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid
  • acide bempedoique
  • acido bempedoico
  • acidum bempedoicum
  • bempedoic acid
  • ESP 55016
  • ESP-55016
  • ETC 1002
  • ETC-1002
  • ETC1002
  • Nexletol
Definition
An α,ω-dicarboxylic acid that is pentadecanedioic acid which is substituted by methyl groups groups at positions 2 and 14, and by a hydroxy group at position 8. It is a drug used for the treatment of high LDL cholesterol, which is sometimes referred to as 'bad cholesterol'.
References
  • cas:738606-46-7
  • drugbank:DB11936
  • kegg.drug:D10691
  • pubmed:23118444
  • pubmed:23709692
  • pubmed:25463109
  • pubmed:26073387
  • pubmed:27138185
  • pubmed:27206943
  • pubmed:27663902
  • pubmed:28064554
  • pubmed:29609755
  • pubmed:29939848
  • pubmed:30586346
  • pubmed:30740643
  • pubmed:30810432
  • pubmed:30865796
  • pubmed:30922146
  • pubmed:30922156
  • pubmed:31202641
  • pubmed:31357887
  • pubmed:31714973
  • pubmed:31714986
  • pubmed:32166726
  • pubmed:32181841
  • pubmed:32314225
  • pubmed:32324179
  • wikipedia.en:Bempedoic_acid
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from bempedoic acid
Phenotype where environments contain bempedoic acid
Phenotype modified by environments containing bempedoic acid
Phenotype affecting bempedoic acid
Human Disease Model