tandospirone

Term ID

CHEBI:145673

Synonyms

(3aR,4S,7R,7aS)-2-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
SM-3997
tandospirona
tandospirone
tandospironum

(all 5)

Definition

A dicarboximide that is (3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione which is substituted by a 4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl group at position 2. It is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM).

References

(all 27)

Ontology

ChEBI ( EBI )

Relationships

is a type of: bridged compound dicarboximide N-alkylpiperazine N-arylpiperazine pyrimidines

bridged compound dicarboximide N-alkylpiperazine N-arylpiperazine pyrimidines Show first 5 Terms
has_role: antidepressant anxiolytic drug

antidepressant anxiolytic drug Show first 5 Terms
inverse is_conjugate_acid_of: tandospirone(1+)

tandospirone(1+) Show first 5 Terms
is_conjugate_base_of: tandospirone(1+)

tandospirone(1+) Show first 5 Terms

Phenotype

Phenotype resulting from tandospirone

Phenotype where environments contain tandospirone

Phenotype modified by environments containing tandospirone

Phenotype affecting tandospirone

Human Disease Model