Search Ontology:
ChEBI

rubimaillin

Term ID
CHEBI:141063
Synonyms
  • methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
  • mollugin
Definition
A benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme.
References
(all 22)
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from rubimaillin
No data available
Phenotype where environments contain rubimaillin
No data available
Phenotype modified by environments containing rubimaillin
Phenotype affecting rubimaillin
No data available
Human Disease Model
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