lasofoxifene

Term ID

CHEBI:135938

Synonyms

(-)-cis-(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
(-)-cis-5,6,7,8-tetrahydro-6-phenyl-5-(p-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2-naphthol
(5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
CP 336156
CP-336,156
CP-336156
lasofoxifene
lasofoxifeno
lasofoxifenum
Oporia

(all 10)

Definition

A member of the class of tetralins that is 5,6,7,8-tetrahydronaphthalen-2-ol in which the hydrogens at positions 5 and 6 are replaced by 4-[2-(pyrrolidin-1-yl)ethoxy]phenyl and phenyl groups, respectively (the 5R,6S-stereoisomer). It is a selective estrogen receptor modulator indicated for the prevention and treatment of osteoporosis in post-menopausal women.

References

(all 22)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether N-alkylpyrrolidine naphthols tetralins

aromatic ether N-alkylpyrrolidine naphthols tetralins Show first 5 Terms
has_role: antineoplastic agent bone density conservation agent cardioprotective agent estrogen receptor agonist estrogen receptor antagonist

antineoplastic agent bone density conservation agent cardioprotective agent estrogen receptor agonist estrogen receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from lasofoxifene

Phenotype where environments contain lasofoxifene

Phenotype modified by environments containing lasofoxifene

Phenotype affecting lasofoxifene

Human Disease Model