beraprost

Term ID

CHEBI:135633

Synonyms

4-{(1R,2R,3aS,8bS)-2-hydroxy-1-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan-5-yl}butanoic acid
beraprost
beraprostum
MDL 201229
MDL-201229
MDL201229
ML 1229
ML-1229
ML1229

(all 9)

Definition

An organic heterotricyclic compound that is (3aS,8bS)-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan in which the hydrogens at positions 1R, 2R and 5 are replaced by (3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl, hydroxy and 3-carboxypropyl groups, respectively. It is a prostaglandin receptor agonist which is approved to treat pulmonary arterial hypertension in Asia.

References

(all 24)

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: enyne monocarboxylic acid organic heterotricyclic compound secondary alcohol secondary allylic alcohol

enyne monocarboxylic acid organic heterotricyclic compound secondary alcohol secondary allylic alcohol Show first 5 Terms
has_role: anti-inflammatory agent antihypertensive agent platelet aggregation inhibitor prostaglandin receptor agonist vasodilator agent

anti-inflammatory agent antihypertensive agent platelet aggregation inhibitor prostaglandin receptor agonist vasodilator agent Show first 5 Terms
inverse is_conjugate_base_of: beraprost(1-)

beraprost(1-) Show first 5 Terms
is_conjugate_acid_of: beraprost(1-)

beraprost(1-) Show first 5 Terms

Phenotype

Phenotype resulting from beraprost

Phenotype where environments contain beraprost

Phenotype modified by environments containing beraprost

Phenotype affecting beraprost

Human Disease Model