venetoclax

Term ID

CHEBI:133021

Synonyms

4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro-4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide
ABT 199
ABT-199
ABT199
GDC 0199
Venclexta
venetoclax

(all 7)

Definition

A member of the class of pyrrolopyridines that is a potent inhibitor of the antiapoptotic protein B-cell lymphoma 2. It is used for treamtment of chronic lymphocytic leukemia with 17p deletion.

References

(all 30)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether C-nitro compound monochlorobenzenes N-alkylpiperazine N-arylpiperazine ... Show All 8 Terms

aromatic ether C-nitro compound monochlorobenzenes N-alkylpiperazine N-arylpiperazine N-sulfonylcarboxamide oxanes pyrrolopyridine Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer B-cell lymphoma 2 inhibitor

antineoplastic agent apoptosis inducer B-cell lymphoma 2 inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from venetoclax

Phenotype where environments contain venetoclax

Phenotype modified by environments containing venetoclax

Phenotype affecting venetoclax

Human Disease Model