Search Ontology:
ChEBI
Ro 5-3335
- Term ID
- CHEBI:131785
- Synonyms
-
- 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-chloro-5-(2-pyrryl)-3H-1,4-benzodiazepin-2(H)-one
- CBFbeta-Runx1 inhibitor II
- Definition
- A 1,4-benzodiazepinone that is nordazepam in which the phenyl substituent has been replaced by a 1H-pyrrol-2-yl group. It inhibits gene expression in HIV-1 at the transcriptional level through interference with Tat-mediated transactivation.
- References
-
- CAS:30195-30-3
- LINCS:LSM-2426
- PMID:1282790
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from Ro 5-3335
Phenotype where environments contain Ro 5-3335
Phenotype modified by environments containing Ro 5-3335
Phenotype affecting Ro 5-3335
Human Disease Model