Search Ontology:
ChEBI
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
- Term ID
- CHEBI:125562
- Synonyms
-
- 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
- 4-dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide
- D237
- histone deacetylase inhibitor III
- M-344
- M344
- N-hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide
- Definition
- A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines.
- References
-
- drugbank:DB02565
- lincs.smallmolecule:LSM-37091
- pubmed:10579829
- pubmed:11831887
- pubmed:16263156
- pubmed:16724231
- pubmed:16773328
- pubmed:20526416
- pubmed:20828393
- pubmed:21854619
- pubmed:22436652
- pubmed:23638461
- pubmed:28380503
- pubmed:29073110
- reaxys:8570090
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Phenotype where environments contain 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Phenotype modified by environments containing 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Phenotype affecting 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Human Disease Model