beta-lapachone

Term ID

CHEBI:10429

Synonyms

• 2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene-5,6-dione
• 3,4-dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione
• ARQ 501
• beta-lap
• beta-Lapachone

Definition

A benzochromenone that is 3,4-dihydro-2H-benzo[h]chromene-5,6-dione substituted by geminal methyl groups at position 2. Isolated from Tabebuia avellanedae, it exhibits antineoplastic and anti-inflammatory activities.

References

• cas:4707-32-8
• kegg.compound:C10367
• knapsack:C00002836
• pubmed:16822200
• pubmed:16891723
• pubmed:18180274
• pubmed:18227145
• pubmed:18424157
• pubmed:18706870
• pubmed:19051226
• pubmed:22560628
• pubmed:22736525
• pubmed:23010281
• pubmed:23071729
• pubmed:23865001
• pubmed:25448047
• pubmed:26328485
• pubmed:3652040
• pubmed:6704108
• reaxys:181499

Ontology

ChEBI  ( EBI )