TALEN

TALEN1-spo11

ID

ZDB-TALEN-190605-1

Name

TALEN1-spo11

Previous Names

None

Target

spo11 (1)

Target Sequence 1

5' - CTAAAGGTGAAGCACC - 3'

Target Sequence 2

5' - TCCAGCAGGATCTATT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
uc73	spo11

Expression

Gene expression in Wild Types + TALEN1-spo11

No data available

Phenotype

Phenotype resulting from TALEN1-spo11

No data available

Phenotype of all Fish created by or utilizing TALEN1-spo11

Phenotype	Fish	Conditions	Figures
testis germ line cell ab1-h2afx labeling absent, abnormal	spo11^uc73/uc73 (AB)	standard conditions	Fig. 7 from Blokhina et al., 2019
testis condensed nuclear chromosome Ab2-sycp1 labeling spatial pattern, abnormal	spo11^uc73/uc73 (AB)	standard conditions	Fig. 8 from Blokhina et al., 2019
ovary condensed nuclear chromosome Ab2-sycp1 labeling spatial pattern, abnormal	spo11^uc73/uc73 (AB)	standard conditions	Fig. 9 from Blokhina et al., 2019
chromosome organization involved in meiotic cell cycle process quality, abnormal	spo11^uc73/uc73 (AB)	standard conditions	Fig. 8 , Fig. 9 from Blokhina et al., 2019
synaptonemal complex organization process quality, abnormal	spo11^uc73/uc73 (AB)	standard conditions	Fig. 8 from Blokhina et al., 2019
meiotic sister chromatid cohesion process quality, abnormal	spo11^uc73/uc73 (AB)	standard conditions	Fig. 8 from Blokhina et al., 2019
spermatocyte synaptonemal structure absent, abnormal	spo11^uc73/uc73 (AB)	standard conditions	Fig. 8 , Fig. 9 from Blokhina et al., 2019
testis sperm absent, abnormal	spo11^uc73/uc73 (NHGRI-1)	standard conditions	Fig. 10 from Blokhina et al., 2019
testis translucent, abnormal	spo11^uc73/uc73 (NHGRI-1)	standard conditions	Fig. 10 from Blokhina et al., 2019
testis germ line cell Ab5-ddx4 labeling spatial pattern, abnormal	spo11^uc73/uc73 (NHGRI-1)	standard conditions	Fig. 10 from Blokhina et al., 2019
whole organism morphology, abnormal	spo11^uc73/+ (NHGRI-1)	standard conditions	Fig. 10 from Blokhina et al., 2019
whole organism morphology, abnormal	spo11^uc73 (NHGRI-1)	standard conditions	Fig. 10 from Blokhina et al., 2019

Citations