CRISPR

CRISPR1-g6pd

ID
ZDB-CRISPR-190115-7
Name
CRISPR1-g6pd
Previous Names
None
Target
Sequence
5' - GAGAAGGGGAGGCAAAACTGG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The gene-specific oligo sequence was 5′-TAATACGACTCACTATAGAGAAGGGGAGGCAAAACTGGTTTTAGAGCTAG AAATAGCAAG-3'.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
No data available
Expression
Gene expression in Wild Types + CRISPR1-g6pd
No data available
Phenotype
Phenotype resulting from CRISPR1-g6pd
Phenotype of all Fish created by or utilizing CRISPR1-g6pd
Phenotype Fish Conditions Figures
blood accumulation pericardial region, abnormal AB + CRISPR1-g6pd chemical treatment: chloroquine, chemical treatment: N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine] Fig. 4 with image from Hwang et al., 2018
whole organism reactive oxygen species increased amount, exacerbated AB + CRISPR1-g6pd chemical treatment: chloroquine Fig. 4 with image from Hwang et al., 2018
glucose-6-phosphate dehydrogenase activity decreased occurrence, abnormal AB + CRISPR1-g6pd chemical treatment: N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine] Fig. 4 with image from Hwang et al., 2018
whole organism reactive oxygen species increased amount, exacerbated AB + CRISPR1-g6pd chemical treatment: chloroquine, chemical treatment: N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine] Fig. 4 with image from Hwang et al., 2018
pericardium edematous, abnormal AB + CRISPR1-g6pd control Fig. 4 with image from Hwang et al., 2018
whole organism NADPH decreased amount, abnormal AB + CRISPR1-g6pd control Fig. 4 with image from Hwang et al., 2018
glucose-6-phosphate dehydrogenase activity decreased occurrence, abnormal AB + CRISPR1-g6pd chemical treatment: chloroquine Fig. 4 with image from Hwang et al., 2018
glucose-6-phosphate dehydrogenase activity decreased occurrence, abnormal AB + CRISPR1-g6pd control Fig. 4 with image from Hwang et al., 2018
whole organism reactive oxygen species increased amount, abnormal AB + CRISPR1-g6pd control Fig. 4 with image from Hwang et al., 2018
pericardium edematous, exacerbated AB + CRISPR1-g6pd chemical treatment: chloroquine Fig. 4 with image from Hwang et al., 2018
pericardium edematous, abnormal AB + CRISPR1-g6pd chemical treatment: chloroquine, chemical treatment: N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine] Fig. 4 with image from Hwang et al., 2018
Citations