CRISPR

CRISPR1-nppb

ID

ZDB-CRISPR-190103-3

Name

CRISPR1-nppb

Previous Names

None

Target

nppb (1)

Sequence

5' - GCAGAAAGATACTCTCTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
uq20ks	nppb
uq21ks	nppb

Expression

Gene expression in Wild Types + CRISPR1-nppb

No data available

Phenotype

Phenotype resulting from CRISPR1-nppb

No data available

Phenotype of all Fish created by or utilizing CRISPR1-nppb

Phenotype	Fish	Conditions	Figures
atrioventricular canal development process quality, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 2 , Fig. 4 from Grassini et al., 2018
atrium tbx2b expression increased distribution, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 2 from Grassini et al., 2018
atrium has2 expression increased distribution, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 2 , Fig. 4 from Grassini et al., 2018
atrium bmp4 expression increased distribution, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 2 from Grassini et al., 2018
atrium vcana expression increased distribution, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 2 from Grassini et al., 2018
heart morphogenesis decreased process quality, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 1 from Grassini et al., 2018
atrium cardiac jelly development process quality, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 2 from Grassini et al., 2018
atrium cardiac jelly increased thickness, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 2 from Grassini et al., 2018
atrium has2 expression mislocalised, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 4 from Grassini et al., 2018
heart edematous, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 1 from Grassini et al., 2018
heart nppb expression decreased amount, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}	standard conditions	Fig. 1 from Grassini et al., 2018
atrium has2 expression position, ameliorated	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks} + MO3-bmp4	standard conditions	Fig. 4 from Grassini et al., 2018
atrium has2 expression spatial pattern, ameliorated	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks} + MO3-bmp4	standard conditions	Fig. 4 from Grassini et al., 2018
atrioventricular canal development process quality, ameliorated	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks} + MO3-bmp4	standard conditions	Fig. 4 from Grassini et al., 2018
atrium cardiac jelly development process quality, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}; uq25bhTg	standard conditions	Fig. 4 from Grassini et al., 2018
atrium cardiac jelly increased thickness, abnormal	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}; uq25bhTg	standard conditions	Fig. 4 from Grassini et al., 2018
atrium cardiac jelly development process quality, ameliorated	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}; uq25bhTg + MO3-bmp4	standard conditions	Fig. 4 from Grassini et al., 2018
atrium cardiac jelly thickness, ameliorated	nppa^{uq19ks/uq19ks}; nppb^{uq20ks/uq20ks}; uq25bhTg + MO3-bmp4	standard conditions	Fig. 4 from Grassini et al., 2018

Citations