CRISPR

CRISPR1-atp6v1h

ID

ZDB-CRISPR-170306-3

Name

CRISPR1-atp6v1h

Previous Names

None

Target

atp6v1h (1)

Sequence

5' - GTGTGTCATCAATCAGGGTCAGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
la439	atp6v1h

Expression

Gene expression in Wild Types + CRISPR1-atp6v1h

No data available

Phenotype

Phenotype resulting from CRISPR1-atp6v1h

No data available

Phenotype of all Fish created by or utilizing CRISPR1-atp6v1h

Phenotype	Fish	Conditions	Figures
bone mineralization process quality, ameliorated	atp6v1h^la439/la439	chemical treatment by environment: EC 3.4.24.35 (gelatinase B) inhibitor	Fig. 4 from Zhang et al., 2017
whole organism mmp13a expression increased amount, abnormal	atp6v1h^la439/la439	standard conditions	Fig. 4 from Zhang et al., 2017
bone mineralization decreased occurrence, abnormal	atp6v1h^la439/la439	standard conditions	Fig. 2 from Zhang et al., 2017
whole organism mmp9 expression increased amount, abnormal	atp6v1h^la439/la439	standard conditions	Fig. 4 from Zhang et al., 2017
cranium mmp9 expression increased amount, abnormal	atp6v1h^la439/la439	standard conditions	Fig. 4 from Zhang et al., 2017
cranium mmp13a expression increased amount, abnormal	atp6v1h^la439/la439	standard conditions	Fig. 4 from Zhang et al., 2017
whole organism decreased life span, abnormal	atp6v1h^la439/la439	standard conditions	Fig. text from Zhang et al., 2017
bone mineralization disrupted, abnormal	atp6v1h^la439/la439	standard conditions	Fig. 2 from Zhang et al., 2017
whole organism dead, abnormal	atp6v1h^la439/la439	standard conditions	Fig. text from Zhang et al., 2017
swim bladder uninflated, abnormal	atp6v1h^la439/la439	standard conditions	Fig. 2 from Zhang et al., 2017
centrum hollow, abnormal	atp6v1h^la439/+	standard conditions	Fig. 3 from Zhang et al., 2017
vertebra decreased size, abnormal	atp6v1h^la439/+	standard conditions	Fig. 3 from Zhang et al., 2017
vertebra morphology, abnormal	atp6v1h^la439/+	standard conditions	Fig. 3 from Zhang et al., 2017
bone mineralization disrupted, abnormal	atp6v1h^la439/+	standard conditions	Fig. 3 from Zhang et al., 2017
trunk curved, abnormal	atp6v1h^la439/+	standard conditions	Fig. 3 from Zhang et al., 2017

Citations