TALEN

TALEN1-mpl

ID

ZDB-TALEN-170804-1

Name

TALEN1-mpl

Previous Names

None

Target

mpl (1)

Target Sequence 1

5' - AGAAGACTTCACTTGCT - 3'

Target Sequence 2

5' - CATAGGACTTTTCAAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
sm10	mpl

Expression

Gene expression in Wild Types + TALEN1-mpl

No data available

Phenotype

Phenotype resulting from TALEN1-mpl

No data available

Phenotype of all Fish created by or utilizing TALEN1-mpl

Phenotype	Fish	Conditions	Figures
head kidney runx1 expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
blood lrrc32 expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
blood itga2b expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
head kidney itga2b expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
whole organism lrrc32 expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
head kidney myb expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
whole organism itga2b expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
head kidney lrrc32 expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
whole organism zfpm1 expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
whole organism gp9 expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
whole organism gp1bb expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
whole organism nfe2 expression decreased amount, abnormal	mpl^sm10/sm10 (AB)	standard conditions	Fig. 1 from Lin et al., 2017
head kidney hematopoietic multipotent progenitor cell decreased amount, abnormal	mpl^sm10/sm10; la2Tg	standard conditions	Fig. 1 from Lin et al., 2017
thrombocyte decreased amount, abnormal	mpl^sm10/sm10; la2Tg	perforation: blood vessel	Fig. 4 from Lin et al., 2017
head kidney thrombocyte decreased amount, abnormal	mpl^sm10/sm10; la2Tg	standard conditions	Fig. 1 from Lin et al., 2017
blood thrombocyte decreased amount, abnormal	mpl^sm10/sm10; la2Tg	standard conditions	Fig. 1 from Lin et al., 2017
thromboblast cell population proliferation decreased occurrence, abnormal	mpl^sm10/sm10; la2Tg	standard conditions	Fig. 2 from Lin et al., 2017
thrombocyte decreased amount, abnormal	mpl^sm10/sm10; la2Tg	standard conditions	Fig. 1, Fig. 3 from Lin et al., 2017
thrombocyte decreased amount, abnormal	mpl^sm10/sm10; la2Tg	chemical treatment by environment: TG101209	Fig. 3 from Lin et al., 2017
thrombocyte cell population proliferation decreased occurrence, abnormal	mpl^sm10/sm10; la2Tg	standard conditions	Fig. 2 from Lin et al., 2017
caudal hematopoietic tissue thrombocyte amount, ameliorated	mpl^sm10/sm10; sm9Tg	chemical treatment by environment: melatonin, chemical treatment by environment: homocysteine	Fig. S10 from Lei et al., 2023
thrombocyte decreased amount, abnormal	mpl^sm10/sm10; sm9Tg	control	Fig. 6 from Lin et al., 2017
thrombocyte decreased amount, abnormal	mpl^sm10/sm10; sm9Tg	standard conditions	Fig. 1 from Lei et al., 2023
caudal hematopoietic tissue thrombocyte increased amount, abnormal	mpl^sm10/sm10; sm9Tg	chemical treatment by environment: homocysteine	Fig. 1 , Fig. S10 from Lei et al., 2023

Citations