CRISPR

CRISPR1-sema3d

ID

ZDB-CRISPR-170202-1

Name

CRISPR1-sema3d

Previous Names

None

Target

sema3d (1)

Sequence

5' - GGAGACAGGTCAGGACGGGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
mu268	sema3d

Expression

Gene expression in Wild Types + CRISPR1-sema3d

No data available

Phenotype

Phenotype resulting from CRISPR1-sema3d

No data available

Phenotype of all Fish created by or utilizing CRISPR1-sema3d

Phenotype	Fish	Conditions	Figures
venous blood vessel morphogenesis decreased process quality, abnormal	sema3d^mu268/mu268; mu240Tg	standard conditions	Fig. 1 , Fig. 8 from Hamm et al., 2016
common cardinal vein actin filament bundle organization decreased process quality, abnormal	sema3d^mu268/mu268; mu240Tg	standard conditions	Fig. 5 , Fig. 8 from Hamm et al., 2016
common cardinal vein blood vessel endothelial cell structure, cavities, abnormal	sema3d^mu268/mu268; mu240Tg	standard conditions	Fig. 8 from Hamm et al., 2016
common cardinal vein actin filament bundle disoriented, abnormal	sema3d^mu268/mu268; mu240Tg	standard conditions	Fig. 5 , Fig. 8 from Hamm et al., 2016
common cardinal vein blood vessel endothelial cell shape, abnormal	sema3d^mu268/mu268; mu240Tg	standard conditions	Fig. 5 from Hamm et al., 2016
common cardinal vein blood vessel endothelium patchy, abnormal	sema3d^mu268/mu268; mu240Tg	standard conditions	Fig. 5 from Hamm et al., 2016
common cardinal vein cell-cell junction decreased length, abnormal	sema3d^mu268/mu268; mu240Tg	standard conditions	Fig. 5 , Fig. 8 from Hamm et al., 2016
common cardinal vein blood vessel endothelial cell disorganized, abnormal	sema3d^mu268/mu268; mu240Tg	standard conditions	Fig. 1 from Hamm et al., 2016
venous blood vessel morphogenesis decreased process quality, abnormal	sema3d^mu268/mu268; s843Tg	standard conditions	Fig. 1 from Hamm et al., 2016
common cardinal vein decreased length, abnormal	sema3d^mu268/mu268; s843Tg	standard conditions	Fig. 1 from Hamm et al., 2016
common cardinal vein increased width, abnormal	sema3d^mu268/mu268; s843Tg	standard conditions	Fig. 1 from Hamm et al., 2016
common cardinal vein blood vessel endothelial cell migration decreased process quality, abnormal	sema3d^mu268/mu268; s843Tg	standard conditions	Fig. 1 from Hamm et al., 2016

Citations