Bugel et al., 2016 - Phenotype anchoring in zebrafish reveals a potential role for matrix metalloproteinases (MMPs) in tamoxifen's effects on skin epithelium. Toxicology and applied pharmacology   296:31-41 Full text @ Tox. App. Pharmacol.
99 Genes / Markers
Marker Type Symbol Name
Gene aifm1 apoptosis inducing factor mitochondrion associated 1
Gene ap1s1 adaptor related protein complex 1 subunit sigma 1
Gene badb BCL2 associated agonist of cell death b
Gene baxa BCL2 associated X, apoptosis regulator a
Gene bsg basigin
Gene calm1b calmodulin 1b
Gene calm2a calmodulin 2a (phosphorylase kinase, delta)
Gene calm2b calmodulin 2b, (phosphorylase kinase, delta)
Gene calm3a calmodulin 3a (phosphorylase kinase, delta)
Gene calm3b calmodulin 3b (phosphorylase kinase, delta)
Gene capn1a calpain 1, (mu/I) large subunit a
Gene capn1b calpain 1, (mu/I) large subunit b
Gene capn2a calpain 2, (m/II) large subunit a
Gene capn2b calpain 2, (m/II) large subunit b
Gene capn3a calpain 3a, (p94)
Gene capn3b calpain 3b
Gene capn5a calpain 5a
Gene capn5b calpain 5b
Gene capn7 calpain 7
Gene capns1a calpain, small subunit 1 a
Gene capns1b calpain, small subunit 1 b
Gene casp2 caspase 2, apoptosis-related cysteine peptidase
Gene casp3a caspase 3, apoptosis-related cysteine peptidase a
Gene casp6a caspase 6, apoptosis-related cysteine peptidase a
Gene casp7 caspase 7, apoptosis-related cysteine peptidase
Gene casp8 caspase 8, apoptosis-related cysteine peptidase
Gene casp9 caspase 9, apoptosis-related cysteine peptidase
Gene cast calpastatin
Gene cdh1 cadherin 1, type 1, E-cadherin (epithelial)
Gene cdh11 cadherin 11, type 2, OB-cadherin (osteoblast)
Gene cdk2 cyclin dependent kinase 2
Gene cdkn1a cyclin dependent kinase inhibitor 1A
Gene crebbpa CREB binding protein a
Gene crebbpb CREB binding protein b
Gene ctnnb1 catenin (cadherin-associated protein), beta 1
Gene ctnnb2 catenin, beta 2
Gene cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b
Gene cyp1a cytochrome P450, family 1, subfamily A
Gene egf epidermal growth factor
Gene epcam epithelial cell adhesion molecule
Gene epoa erythropoietin a
Gene esr1 estrogen receptor 1
Gene esr2a estrogen receptor 2a
Gene esr2b estrogen receptor 2b
Gene fgf7 fibroblast growth factor 7
Gene fosab v-fos FBJ murine osteosarcoma viral oncogene homolog Ab
Gene gsk3ba glycogen synthase kinase 3 beta, genome duplicate a
Gene gstp1.1 glutathione S-transferase pi 1.1
Gene hif1aa hypoxia inducible factor 1 subunit alpha a
Gene hif1ab hypoxia inducible factor 1 subunit alpha b
Gene hif1al hypoxia inducible factor 1 subunit alpha, like
Gene hif1al2 hypoxia inducible factor 1 subunit alpha, like 2
Gene igf1 insulin-like growth factor 1
Gene igf2a insulin-like growth factor 2a
Gene igf2b insulin-like growth factor 2b
Gene igf3 insulin-like growth factor 3
Gene igfbp1a insulin-like growth factor binding protein 1a
Gene igfbp1b insulin-like growth factor binding protein 1b
Gene jun Jun proto-oncogene, AP-1 transcription factor subunit
Gene kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Gene lhb luteinizing hormone subunit beta
Gene mapk3 mitogen-activated protein kinase 3
Gene mitfa melanocyte inducing transcription factor a
Gene mmp11a matrix metallopeptidase 11a
Gene mmp11b matrix metallopeptidase 11b
Gene mmp13a matrix metallopeptidase 13a
Gene mmp13b matrix metallopeptidase 13b
Gene mmp14a matrix metallopeptidase 14a (membrane-inserted)
Gene mmp14b matrix metallopeptidase 14b (membrane-inserted)
Gene mmp15a matrix metallopeptidase 15a
Gene mmp16a matrix metallopeptidase 16a (membrane-inserted)
Gene mmp16b matrix metallopeptidase 16b (membrane-inserted)
Gene mmp17a matrix metallopeptidase 17a
Gene mmp17b matrix metallopeptidase 17b
Gene mmp2 matrix metallopeptidase 2
Gene mmp9 matrix metallopeptidase 9
Gene myca MYC proto-oncogene, bHLH transcription factor a
Gene nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Gene prkcaa protein kinase C, alpha, a
Gene prkcba protein kinase C, beta a
Gene prkcbb protein kinase C, beta b
Gene prkcg protein kinase C, gamma
Gene tbxta T-box transcription factor Ta
Gene tbxtb T-box transcription factor Tb
Gene tcf20 transcription factor 20
Gene tgfa transforming growth factor, alpha
Gene tgfb3 transforming growth factor, beta 3
Gene timp2a TIMP metallopeptidase inhibitor 2a
Gene timp2b TIMP metallopeptidase inhibitor 2b
Gene timp4.1 TIMP metallopeptidase inhibitor 4, tandem duplicate 1
Gene tnfa tumor necrosis factor a (TNF superfamily, member 2)
Gene tnfb tumor necrosis factor b (TNF superfamily, member 2)
Gene tp53 tumor protein p53
Gene tp63 tumor protein p63
Gene vegfaa vascular endothelial growth factor Aa
Gene vegfab vascular endothelial growth factor Ab
Gene vtg1 vitellogenin 1
Gene wnt3a wingless-type MMTV integration site family, member 3A
Gene wnt8a wingless-type MMTV integration site family, member 8a
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