Amsterdam et al., 2004 - Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America   101(35):12792-12797 Full text @ Proc. Natl. Acad. Sci. USA
316 Genes / Markers
Marker Type Symbol Name
Gene abce1 ATP-binding cassette, sub-family E (OABP), member 1
Gene abhd11 abhydrolase domain containing 11
Gene actl6a actin-like 6A
Gene adssl adenylosuccinate synthase, like
Gene airim AFG2 interacting ribosome maturation factor
Gene arl13b ADP-ribosylation factor-like 13b
Gene arnt2 aryl-hydrocarbon receptor nuclear translocator 2
Gene atp1a1a.1 ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 1
Gene atp5po ATP synthase peripheral stalk subunit OSCP
Gene atp6ap1b ATPase H+ transporting accessory protein 1b
Gene atp6ap2 ATPase H+ transporting accessory protein 2
Gene atp6v0ca ATPase H+ transporting V0 subunit ca
Gene atp6v0d1 ATPase H+ transporting V0 subunit d1
Gene atp6v1e1b ATPase H+ transporting V1 subunit E1b
Gene atp6v1f ATPase H+ transporting V1 subunit F
Gene atp6v1h ATPase H+ transporting V1 subunit H
Gene aurkb aurora kinase B
Gene b3gat3 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
Gene b4galt7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
Gene birc2 baculoviral IAP repeat containing 2
Gene birc5a baculoviral IAP repeat containing 5a
Gene bud31 BUD31 homolog
Gene bysl bystin-like
Gene cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Gene capzb capping actin protein of muscle Z-line subunit beta
Gene ccm2 CCM2 scaffold protein
Gene ccna2 cyclin A2
Gene ccnb1 cyclin B1
Gene cct2 chaperonin containing TCP1, subunit 2 (beta)
Gene cct3 chaperonin containing TCP1, subunit 3 (gamma)
Gene cct5 chaperonin containing TCP1, subunit 5 (epsilon)
Gene cct7 chaperonin containing TCP1, subunit 7 (eta)
Gene cdc37 cell division cycle 37 homolog (S. cerevisiae)
Gene cdh2 cadherin 2, type 1, N-cadherin (neuronal)
Gene cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
Gene cdk1 cyclin dependent kinase 1
Gene cdx4 caudal type homeobox 4
Gene cenpl centromere protein L
Gene cenpn centromere protein N
Gene cfap298 cilia and flagella associated protein 298
Gene chmp2a charged multivesicular body protein 2A
Gene chmp6b charged multivesicular body protein 6b
Gene chrd chordin
Gene clasp1b cytoplasmic linker associated protein 1b
Gene cldnj claudin j
Gene clint1a clathrin interactor 1a
Gene cltca clathrin, heavy chain a (Hc)
Gene cluap1 clusterin associated protein 1
Gene cnot1 CCR4-NOT transcription complex, subunit 1
Gene copa COPI coat complex subunit alpha
Gene copz1 COPI coat complex subunit zeta 1
Gene cpsf1 cleavage and polyadenylation specific factor 1
Gene cpsf3 cleavage and polyadenylation specific factor 3
Gene cpsf4 cleavage and polyadenylation specific factor 4
Gene csnk1a1 casein kinase 1, alpha 1
Gene cstf3 cleavage stimulation factor, 3' pre-RNA, subunit 3
Gene ctdp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Gene cwc25 CWC25 spliceosome associated protein homolog
Gene dcaf7 ddb1 and cul4 associated factor 7
Gene ddx18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Gene ddx19b DEAD-box helicase 19b
Gene ddx27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
Gene ddx51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
Gene ddx54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Gene ddx55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Gene ddx56 DEAD (Asp-Glu-Ala-Asp) box helicase 56
Gene dhx16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
Gene dla deltaA
Gene dlst dihydrolipoamide S-succinyltransferase
Gene dmap1 DNA methyltransferase 1 associated protein 1
Gene dnaaf11 dynein axonemal assembly factor 11
Gene dnaaf6 dynein axonemal assembly factor 6
Gene dpy19l1l dpy-19-like 1, like (H. sapiens)
Gene dtl denticleless E3 ubiquitin protein ligase homolog (Drosophila)
Gene ebna1bp2 EBNA1 binding protein 2
Gene ect2 epithelial cell transforming 2
Gene eef1a1l1 eukaryotic translation elongation factor 1 alpha 1, like 1
Gene eef1g eukaryotic translation elongation factor 1 gamma
Gene eif2s3 eukaryotic translation initiation factor 2, subunit 3 gamma
Gene eif3d eukaryotic translation initiation factor 3, subunit D
Gene eif3ea eukaryotic translation initiation factor 3, subunit E, a
Gene eif3g eukaryotic translation initiation factor 3, subunit G
Gene eif4a1a eukaryotic translation initiation factor 4A1A
Gene epcam epithelial cell adhesion molecule
Gene esco2 establishment of sister chromatid cohesion N-acetyltransferase 2
Gene exoc2 exocyst complex component 2
Gene exosc4 exosome component 4
Gene exosc8 exosome component 8
Gene eya1 EYA transcriptional coactivator and phosphatase 1
Gene fbl fibrillarin
Gene fbxo5 F-box protein 5
Gene fen1 flap structure-specific endonuclease 1
Gene foxi1 forkhead box i1
Gene get1 guided entry of tail-anchored proteins factor 1
Gene gins3 GINS complex subunit 3
Gene gle1 GLE1 RNA export mediator
Gene gnl3 G protein nucleolar 3
Gene gnl3l G protein nucleolar 3 like
Gene gpc4 glypican 4
Gene gtf3aa general transcription factor IIIAa
Gene gtpbp4 GTP binding protein 4
Gene hdac1 histone deacetylase 1
Gene hdac3 histone deacetylase 3
Gene heatr1 HEAT repeat containing 1
Gene hinfp histone H4 transcription factor
Gene hnf1ba HNF1 homeobox Ba
Gene hspa5 heat shock protein 5
Gene hspa8 heat shock protein 8
Gene hspa9 heat shock protein 9
Gene ift172 intraflagellar transport 172
Gene ift57 intraflagellar transport 57 homolog (Chlamydomonas)
Gene ift81 intraflagellar transport 81 homolog
Gene ints7 integrator complex subunit 7
Gene kars1 lysyl-tRNA synthetase 1
Gene kif11 kinesin family member 11
Gene kif23 kinesin family member 23
Gene kri1 KRI1 homolog
Gene lamb1a laminin, beta 1a
Gene lamc1 laminin, gamma 1
Gene lman2la lectin, mannose-binding 2-like a
Gene ltv1 LTV1 ribosome biogenesis factor
Gene mak16 MAK16 homolog (S. cerevisiae)
Gene mars1 methionyl-tRNA synthetase 1
Gene mbtps1 membrane-bound transcription factor peptidase, site 1
Gene mcm2 minichromosome maintenance complex component 2
Gene mcm3 minichromosome maintenance complex component 3
Gene mcm3ap minichromosome maintenance complex component 3 associated protein
Gene mcm7 minichromosome maintenance complex component 7
Gene med14 mediator complex subunit 14
Gene med19b mediator complex subunit 19b
Gene med29 mediator complex subunit 29
Gene mib1 MIB E3 ubiquitin protein ligase 1
Gene mybbp1a MYB binding protein (P160) 1a
Gene mybl2b v-myb avian myeloblastosis viral oncogene homolog-like 2b
Gene naca nascent polypeptide associated complex subunit alpha
Gene ncbp2 nuclear cap binding protein subunit 2
Gene ncl nucleolin
Gene ndc80 NDC80 kinetochore complex component
Gene ndr1 nodal-related 1
Gene ndr2 nodal-related 2
Gene ndufs5 NADH:ubiquinone oxidoreductase subunit S5
Gene neurog1 neurogenin 1
Gene nf2b NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor b
Gene nfyc nuclear transcription factor Y, gamma
Gene nifk nucleolar protein interacting with the FHA domain of MKI67
Gene nkap NFKB activating protein
Gene noc2l NOC2-like nucleolar associated transcriptional repressor
Gene noc3l NOC3-like DNA replication regulator
Gene nol10 nucleolar protein 10
Gene nop10 NOP10 ribonucleoprotein homolog (yeast)
Gene nop14 NOP14 nucleolar protein homolog (yeast)
Gene nop56 NOP56 ribonucleoprotein homolog
Gene nop58 NOP58 ribonucleoprotein homolog (yeast)
Gene notch1a notch receptor 1a
Gene nrf1 nuclear respiratory factor 1
Gene nuf2 UF2 component of NDC80 kinetochore complex
Gene nup205 nucleoporin 205
Gene nup93 nucleoporin 93
Gene nxf1b nuclear RNA export factor 1b
Gene odc1 ornithine decarboxylase 1
Gene pabpc1a poly(A) binding protein, cytoplasmic 1a
Gene paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Gene pals1a protein associated with LIN7 1, MAGUK p55 family member a
Gene parvaa parvin, alpha a
Gene pbx4 pre-B-cell leukemia transcription factor 4
Gene pdcd7 programmed cell death 7
Gene pes pescadillo
Gene phf5a PHD finger protein 5A
Gene pho phoenix
Gene pkd2 polycystic kidney disease 2
Gene plcg1 phospholipase C, gamma 1
Gene plk1 polo-like kinase 1 (Drosophila)
Gene plrg1 pleiotropic regulator 1
Gene pola1 polymerase (DNA directed), alpha 1
Gene polb polymerase (DNA directed), beta
Gene pole2 polymerase (DNA directed), epsilon 2
Gene polr1a RNA polymerase I subunit A
Gene polr1c RNA polymerase I and III subunit C
Gene polr1d RNA polymerase I and III subunit D
Gene polr1f RNA polymerase I subunit F
Gene polr2b RNA polymerase II subunit B
Gene polr2d RNA polymerase II subunit D
Gene polr2g RNA polymerase II subunit G
Gene polr3f polymerase (RNA) III (DNA directed) polypeptide F
Gene pou5f3 POU domain, class 5, transcription factor 3
Gene ppp1r12a protein phosphatase 1, regulatory subunit 12A
Gene prdm5 PR domain containing 5
Gene prkci protein kinase C, iota
Gene prpf3 PRP3 pre-mRNA processing factor 3 homolog (yeast)
Gene psmb1 proteasome 20S subunit beta 1
Gene psmc6 proteasome 26S subunit, ATPase 6
Gene qars1 glutaminyl-tRNA synthetase 1
Gene rad21a RAD21 cohesin complex component a
Gene rae1 ribonucleic acid export 1
Gene rbbp6 retinoblastoma binding protein 6
Gene rbm19 RNA binding motif protein 19
Gene rbm22 RNA binding motif protein 22
Gene rbm42 RNA binding motif protein 42
Gene rcl1 RNA terminal phosphate cyclase-like 1
Gene rfc4 replication factor C (activator 1) 4
Gene rfc5 replication factor C (activator 1) 5
Gene ric8b RIC8 guanine nucleotide exchange factor B
Gene rnf113a ring finger protein 113A
Gene rngtt RNA guanylyltransferase and 5'-phosphatase
Gene rpa1 replication protein A1
Gene rpl11 ribosomal protein L11
Gene rpl12 ribosomal protein L12
Gene rpl13 ribosomal protein L13
Gene rpl14 ribosomal protein L14
Gene rpl19 ribosomal protein L19
Gene rpl24 ribosomal protein L24
Gene rpl28 ribosomal protein L28
Gene rpl3 ribosomal protein L3
Gene rpl35 ribosomal protein L35
Gene rpl36 ribosomal protein L36
Gene rpl36a ribosomal protein L36A
Gene rpl6 ribosomal protein L6
Gene rpl7 ribosomal protein L7
Gene rpl7l1 ribosomal protein L7-like 1
Gene rpl9 ribosomal protein L9
Gene rplp1 ribosomal protein lateral stalk subunit P1
Gene rpn2 ribophorin II
Gene rprd1b regulation of nuclear pre-mRNA domain containing 1B
Gene rps11 ribosomal protein S11
Gene rps12 ribosomal protein S12
Gene rps15 ribosomal protein S15
Gene rps15a ribosomal protein S15a
Gene rps18 ribosomal protein S18
Gene rps29 ribosomal protein S29
Gene rps3a ribosomal protein S3A
Gene rps5 ribosomal protein S5
Gene rps7 ribosomal protein S7
Gene rps8a ribosomal protein S8a
Gene rpsa ribosomal protein SA
Gene rrm1 ribonucleotide reductase M1 polypeptide
Gene rrm2 ribonucleotide reductase M2 polypeptide
Gene rrp1 ribosomal RNA processing 1
Gene ruvbl1 RuvB-like AAA ATPase 1
Gene ruvbl2 RuvB-like AAA ATPase 2
Gene sars1 seryl-tRNA synthetase 1
Gene scarb2a scavenger receptor class B, member 2a
Gene sdad1 SDA1 domain containing 1
Gene sec61a1a SEC61 translocon subunit alpha 1a
Gene selenoh selenoprotein H
Gene sf1 splicing factor 1
Gene sf3a3 splicing factor 3a, subunit 3
Gene sf3b1 splicing factor 3b, subunit 1
Gene sf3b4 splicing factor 3b, subunit 4
Gene sf3b5 splicing factor 3b, subunit 5
Gene sfpq splicing factor proline/glutamine-rich
Gene si:ch211-114c12.2 si:ch211-114c12.2
Gene skp1 S-phase kinase-associated protein 1
Gene slc25a24l solute carrier family 25 member 24, like
Gene slc25a5 solute carrier family 25 member 5
Gene slc35d1a solute carrier family 35 member D1a
Gene smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Gene smc1al structural maintenance of chromosomes 1A, like
Gene smc4 structural maintenance of chromosomes 4
Gene smo smoothened, frizzled class receptor
Gene snrnp70 small nuclear ribonucleoprotein 70 (U1)
Gene snrpc small nuclear ribonucleoprotein polypeptide C
Gene snrpd1 small nuclear ribonucleoprotein D1 polypeptide
Gene snrpf small nuclear ribonucleoprotein polypeptide F
Gene snw1 SNW domain containing 1
Gene sox9a SRY-box transcription factor 9a
Gene spint1a serine peptidase inhibitor, Kunitz type 1 a
Gene spns1 SPNS lysolipid transporter 1, lysophospholipid
Gene srp68 signal recognition particle 68
Gene srrt serrate RNA effector molecule homolog (Arabidopsis)
Gene stil STIL centriolar assembly protein
Gene stxbp3 syntaxin binding protein 3
Gene suds3 SDS3 homolog, SIN3A corepressor complex component
Gene supt6h SPT6 homolog, histone chaperone and transcription elongation factor
Gene surf6 surfeit 6
Gene taf1b TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
Gene taf2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Gene taf7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Gene taf8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Gene tbx16 T-box transcription factor 16
Gene tcp1 t-complex 1
Gene terfa telomeric repeat binding factor a
Gene thoc2 THO complex 2
Gene ticrr TopBP1-interacting, checkpoint, and replication regulator
Gene timm23a translocase of inner mitochondrial membrane 23 homolog a (yeast)
Gene top2a DNA topoisomerase II alpha
Gene trappc11 trafficking protein particle complex subunit 11
Gene trim25l tripartite motif containing 25, like
Gene trnt1 tRNA nucleotidyl transferase, CCA-adding, 1
Gene tsr2 TSR2 ribosome maturation factor
Gene ttc27 tetratricopeptide repeat domain 27
Gene tubg1 tubulin, gamma 1
Gene tyms thymidylate synthetase
Gene u2af1 U2 small nuclear RNA auxiliary factor 1
Gene ufd1l ubiquitin recognition factor in ER associated degradation 1
Gene uhrf1 ubiquitin-like with PHD and ring finger domains 1
Gene uspl1 ubiquitin specific peptidase like 1
Gene utp11 UTP11 small subunit processome component
Gene utp15 UTP15 small subunit processome component
Gene utp25 UTP25 small subunit processor component
Gene uxs1 UDP-glucuronate decarboxylase 1
Gene vars1 valyl-tRNA synthetase 1
Gene vps18 VPS18 core subunit of CORVET and HOPS complexes
Gene wdr1 WD repeat domain 1
Gene wdr12 WD repeat domain 12
Gene wdr33 WD repeat domain 33
Gene wdr36 WD repeat domain 36
Gene wdr43 WD repeat domain 43
Gene wdr46 WD repeat domain 46
Gene wdr55 WD repeat domain 55
Gene wdr75 WD repeat domain 75
Gene wdr82 WD repeat domain 82
Gene wee1 WEE1 G2 checkpoint kinase
Gene wnt5b wingless-type MMTV integration site family, member 5b
Gene zc4h2 zinc finger, C4H2 domain containing
Gene zcchc7 zinc finger, CCHC domain containing 7
Gene zmat2 zinc finger, matrin-type 2