Gene
cdk8
- ID
- ZDB-GENE-030903-2
- Name
- cyclin dependent kinase 8
- Symbol
- cdk8 Nomenclature History
- Previous Names
-
- wu:fk95h11
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to localize to mediator complex. Orthologous to human CDK8 (cyclin dependent kinase 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147230 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with hypotonia and behavioral abnormalities | 618748 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:A8E4S2
|
465 | ||||
|
UniProtKB:Q8JH47
|
464 | ||||
|
UniProtKB:A0A8M2B9W5
|
468 |
Interactions and Pathways
No data available
Plasmids
No data available