ZFIN Person: Lam, Pui Ying

ZFIN ID: ZDB-PERS-100617-7

Lam, Pui Ying

Email:	plam@mcw.edu
URL:	https://www.mcw.edu/departments/cell-biology-neurobiology-and-anatomy/people/pui-ying-penny-lam-phd
Affiliation:	Pui Ying Lam Lab
Address:	Medical College of Wisconsin, 8701 W Watertown Plank Rd, CB067, Wauwatosa, WI 53226-3548 USA
Country:	United States
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Sampieri, A., Padilla-Flores, T., Thawani, A.R., Lam, P.Y., Fuchter, M.J., Peterson, R., Vaca, L. (2023) The conducting state of TRPA1 modulates channel lateral mobility. Cell Calcium. 116:102800102800

Houseright, R.A., Rosowski, E.E., Lam, P.Y., Tauzin, S.J.M., Mulvaney, O., Dewey, C.N., Huttenlocher, A. (2020) Cell type specific gene expression profiling reveals a role for complement component C3 in neutrophil responses to tissue damage. Scientific Reports. 10:15716

Lam, P.Y., Thawani, A.R., Balderas, E., White, A.J.P., Chaudhuri, D., Fuchter, M.J., Peterson, R. (2020) TRPswitch - a step function chemo-optogenetic ligand for the vertebrate TRPA1 channel. Journal of the American Chemical Society. 142(41):17457-17468

Lam, P.Y., Kutchukian, P., Anand, R., Imbriglio, J., Andrews, C., Padilla, H., Vohra, A., Lane, S., Parker, D.L., Taracido, I.C., Johns, D.G., Beerens, M., MacRae, C.A., Caldwell, J., Sorota, S., Asnani, A., Peterson, R.T. (2020) Cyp1 inhibition prevents doxorubicin-induced cardiomyopathy in a zebrafish heart failure model. Chembiochem : a European journal of chemical biology. 21(13):1905-1910

Tsai, T.Y., Collins, S.R., Chan, C.K., Hadjitheodorou, A., Lam, P.Y., Lou, S.S., Yang, H.W., Jorgensen, J., Ellett, F., Irimia, D., Davidson, M.W., Fischer, R.S., Huttenlocher, A., Meyer, T., Ferrell, J.E., Theriot, J.A. (2019) Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization. Developmental Cell. 49:189-205.e6

Lam, P.Y., Peterson, R.T. (2019) Developing zebrafish disease models for in vivo small molecule screens. Current Opinion in Chemical Biology. 50:37-44

Fischer, R.S., Lam, P.Y., Huttenlocher, A., Waterman, C.M. (2018) Filopodia and focal adhesions: An integrated system driving branching morphogenesis in neuronal pathfinding and angiogenesis. Developmental Biology. 451(1):86-95

Jin, Y.N., Schlueter, P.J., Jurisch-Yaksi, N., Lam, P.Y., Jin, S., Hwang, W.Y., Yeh, J.J., Yoshigi, M., Ong, S.E., Schenone, M., Hartigan, C.R., Carr, S.A., Peterson, R.T. (2018) Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells. Nature Chemical Biology. 14(9):844-852

Barros-Becker, F., Lam, P.Y., Fisher, R., Huttenlocher, A. (2017) Live imaging reveals distinct modes of neutrophil and macrophage migration within interstitial tissues. Journal of Cell Science. 130(22):3801-3808

Lam, P.Y., Mendu, S.K., Mills, R.W., Zheng, B., Padilla, H., Milan, D.J., Desai, B.N., Peterson, R.T. (2017) A high-conductance chemo-optogenetic system based on the vertebrate channel Trpa1b. Scientific Reports. 7:11839

Vincent, W.J., Freisinger, C.M., Lam, P.Y., Huttenlocher, A., Sauer, J.D. (2016) Macrophages mediate flagellin induced inflammasome activation and host defense in zebrafish. Cellular Microbiology. 18(4):591-604

Lam, P.Y., Mangos, S., Green, J.M., Reiser, J., Huttenlocher, A. (2015) In vivo imaging and characterization of actin microridges. PLoS One. 10:e0115639

Tauzin, S., Starnes, T.W., Becker, F.B., Lam, P.Y., Huttenlocher, A. (2014) Redox and Src family kinase signaling control leukocyte wound attraction and neutrophil reverse migration. The Journal of cell biology. 207:589-98

Lam, P.Y., Fischer, R.S., Shin, W.D., Waterman, C.M., and Huttenlocher, A. (2014) Spinning disk confocal imaging of neutrophil migration in zebrafish. Methods in molecular biology (Clifton, N.J.). 1124:219-233

Lam, P.Y., Harvie, E.A., and Huttenlocher, A. (2013) Heat shock modulates neutrophil motility in zebrafish. PLoS One. 8(12):e84436

Lam, P.Y., Kamei, C.N., Mangos, S., Mudumana, S., Liu, Y., and Drummond, I.A. (2013) odd-skipped related 2 is required for fin chondrogenesis in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(11):1284-92

Yoo, S.K., Lam, P.Y., Eichelberg, M.R., Zasadil, L., Bement, W.M., and Huttenlocher, A. (2012) The role of microtubules in neutrophil polarity and migration in live zebrafish. Journal of Cell Science. 125(23):5702-5710

Lam, P.Y., Yoo, S.K., Green, J.M., and Huttenlocher, A. (2012) The SH2-domain-containing inositol 5-phosphatase (SHIP) limits neutrophil motility and wound recruitment in zebrafish. Journal of Cell Science. 125(21):4973-4978

Mangos, S., Lam, P.Y., Zhao, A., Liu, Y., Mudumana, S., Vasilyev, A., Liu, A., and Drummond, I.A. (2010) The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation. Disease models & mechanisms. 3(5-6):354-365

Lam, P.Y., Webb, S.E., Leclerc, C., Moreau, M., and Miller, A.L. (2009) Inhibition of stored Ca release disrupts convergence-related cell movements in the lateral intermediate mesoderm resulting in abnormal positioning and morphology of the pronephric anlagen in intact zebrafish embryos. Development, growth & differentiation. 51(4):429-442

Vasilyev, A., Liu, Y., Mudumana, S., Mangos, S., Lam, P.Y., Majumdar, A., Zhao, J., Poon, K.L., Kondrychyn, I., Korzh, V., and Drummond, I.A. (2009) Collective Cell Migration Drives Morphogenesis of the Kidney Nephron. PLoS Biology. 7(1):e9

NON-ZEBRAFISH PUBLICATIONS