| Name: | granuloma formation |
|---|---|
| Synonyms: | |
| Definition: | The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. |
| Ontology: | GO: Biological Process [GO:0002432] QuickGO AmiGO |
| Name: | decreased occurrence |
|---|---|
| Synonyms: | decreased incidence |
| Definition: | An occurrence which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002052] |