OBO ID: GO:1990270
Term Name: platelet-derived growth factor receptor-ligand complex Search Ontology:
Synonyms:
  • PDGF receptor-ligand complex
  • PDGF-AA-receptor alpha complex
  • PDGF-AB-receptor alpha complex
  • PDGF-AB-receptor beta complex
  • PDGF-BB-receptor alpha complex
  • PDGF-BB-receptor alpha-beta complex
  • PDGF-BB-receptor beta complex
  • PDGF-CC-receptor alpha complex
  • PDGF-CC-receptor alpha-beta complex
  • PDGF-CC-receptor beta complex
  • PDGF-DD-receptor alpha-beta complex
  • PDGF-DD-receptor beta complex
  • receptor-ligand complex
Definition: A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes. 11331882
References:
Ontology: GO: Cellular Component    QuickGO    AmiGO
EXPRESSION No data available
PHENOTYPE No data available