OBO ID: GO:0120123
Term Name: ubiquitin activating enzyme complex Search Ontology:
Synonyms:
  • E1 complex
Definition: A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate. 9545234
References:
Ontology: GO: Cellular Component    QuickGO    AmiGO
EXPRESSION No data available
PHENOTYPE No data available